Helicobacter pylori Accumulates Photoactive Porphyrins and Is Killed by Visible Light

Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light.

Helicobacter pylori colonizes the mucus layer of the human stomach and duodenum, causes chronic gastritis, gastric ulcer, and is a risk factor for gastric adenocarcinoma. There is a 20% failure rate in antibiotic therapy, which is increasingly due to antibiotic resistance and necessitates the search for alternative antimicrobial methods. We have discovered that H. pylori when cultured in liquid...

Helicobacter pylori is killed by nitrite under acidic conditions.

BACKGROUND Due to the expression of urease, Helicobacter pylori is able to establish itself in the human stomach under acidic conditions. A novel host defence mechanism was recently proposed, suggesting that the formation of salivary nitrite in symbiosis with facultative anaerobic bacteria in the oropharynx, is aimed at enhancing the antimicrobial activity of gastric juice. AIMS To investigat...

Helicobacter pylori and Migraine: Is Eradication of Helicobacter pylori Effective in Relief of Migraine Headache?

Background: Association between Helicobacter pylori (HP) infection and migraine and the effect of HP eradication on relief of migraine headache have been studied but the results are controversial. Objectives: To evaluate the effect of HP eradication in treatment of patients affected by migraine. Materials and Methods: Eighty consecutive HP infected patients affected by migraine without au...

Helicobacter pylori Infection and Light Chain Gammopathy

OBJECTIVE Helicobacter pylori provokes a host of immune alterations upon colonizing the gastric mucosa. DESIGN We report 22 individuals with confirmed Helicobacter pylori infection who were also managed for the concurrent elevation of immunoglobulin free light chain (kappa and lambda) levels. RESULT Of the 22 patients, 15 patients (68.2%) had elevated free light chain levels: 6 patients (40...

The only good Helicobacter pylori is a dead Helicobacter pylori.